A common side effect of progestin-only contraceptives is:

• A. Depression
• B. Amenorrhea
• C. Hypertension
• D. Edema

Answer: (B)

Progestin-only contraceptives, also known as the "mini-pill," primarily work by thickening cervical mucus and preventing ovulation. One of the notable side effects often associated with these contraceptives is amenorrhea, which is the absence of menstruation. This can happen because progestin can alter the normal menstrual cycle, sometimes leading to irregularities or cessation of periods altogether.

The mechanism behind amenorrhea with progestin-only methods relates to hormonal changes that can cause the uterine lining to become thinner, reducing or eliminating menstrual bleeding. Many women appreciate this feature, especially those who experience significant discomfort, heavy bleeding, or other menstrual-related issues.

While depression, hypertension, and edema can also be potential side effects of hormonal contraceptives in some cases, they are not as commonly associated specifically with progestin-only methods compared to amenorrhea. Thus, amenorrhea stands out as a common and notable side effect of progestin-only contraceptives.