Medroxyprogesterone acetate (Provera) reduces abnormal uterine bleeding by:

• A. Preventing overgrowth of the endometrium
• B. Halting the production of estrogen
• C. Stimulating FSH production
• D. Maintaining the corpus luteum

Answer: (A)

Medroxyprogesterone acetate (Provera) is a synthetic progestin that plays a crucial role in regulating uterine bleeding. One of its primary mechanisms is the prevention of overgrowth of the endometrium. By providing progestational activity, it counteracts the effects of estrogen, which is responsible for stimulating the growth of the endometrial lining.

When the endometrial tissue undergoes excessive proliferation due to unopposed estrogen, it can lead to abnormal uterine bleeding. By administering medroxyprogesterone acetate, the endometrium is maintained in a more stable state, reducing the incidence of heavy or irregular bleeding. This is particularly beneficial in conditions such as dysfunctional uterine bleeding, where hormonal imbalances lead to an excess of estrogen without sufficient progesterone to balance it.

Other options presented do not accurately capture the primary action of medroxyprogesterone acetate in this context. For instance, halting estrogen production does not directly relate to its function, as medroxyprogesterone does not inhibit estrogen synthesis but rather modulates the effects of estrogen on the endometrium. Similarly, stimulating FSH production and maintaining the corpus luteum are not central to how this medication functions to reduce abnormal uterine