One benefit of using medroxyprogesterone acetate (Depo-Provera) is a decreased risk of which condition?

• A. Cardiovascular complications
• B. Pulmonary hypertension
• C. Weight gain
• D. Pelvic inflammatory disease

Answer: (D)

Medroxyprogesterone acetate, commonly known as Depo-Provera, is a contraceptive administered via injection that contains a progestin hormone. One significant benefit of using this medication is its association with a decreased risk of pelvic inflammatory disease (PID).

PID is an infection of the female reproductive organs that can lead to serious complications, including infertility, chronic pelvic pain, and ectopic pregnancies. The use of Depo-Provera helps to prevent ovulation and alters the endometrial lining, making it inhospitable for sperm and potentially harmful bacteria. Additionally, the thickening of cervical mucus acts as a barrier, which can reduce the likelihood of infections ascending from the vagina into the uterus and other reproductive organs, thus lowering the risk of PID.

While the other options mention conditions or side effects that may be experienced during the use of hormonal contraceptives, the direct preventive effect of Depo-Provera on pelvic inflammatory disease is a well-documented benefit that sets it apart in the context of women's reproductive health.