What medication is indicated for the treatment of endometriosis?

• A. GnRH agonists
• B. Oral contraceptives
• C. Metronidazole
• D. Clomiphene citrate

Answer: (A)

GnRH agonists are indicated for the treatment of endometriosis because they work by suppressing ovarian hormone production, leading to a decreased level of estrogen, which is known to stimulate endometrial tissue growth. By inhibiting the effects of estrogen, GnRH agonists can help reduce the size of endometriotic lesions and alleviate related symptoms such as pelvic pain and dysmenorrhea.

Oral contraceptives can also be used in the management of endometriosis, as they help in controlling menstrual cycles and reducing menstrual flow, which can lessen the symptoms associated with the condition. However, GnRH agonists are often preferred for more severe cases or when medical treatment is necessary to induce a temporary state of menopause.

Metronidazole is an antibiotic primarily used for infections and is not indicated for endometriosis treatment, while Clomiphene citrate is used for ovulation induction in infertility and is not relevant for managing endometriosis itself. Thus, the use of GnRH agonists specifically targets the hormonal pathways involved in endometriosis, making them the most suitable choice in this context.