Which hormonal treatment is indicated for a woman with endometriosis?

• A. Testosterone replacement
• B. Low-dose oral estrogen
• C. Androgen therapy
• D. Combination contraceptives

Answer: (C)

The appropriate hormonal treatment for endometriosis involves the use of combination contraceptives. These contraceptives typically contain both estrogen and progestin, which can help suppress the hormonal cycle that contributes to endometrial tissue growth outside the uterus. By regulating or stopping menstruation, combination contraceptives reduce the occurrence of pain, control bleeding, and can lead to a reduction in endometrial lesions.

Moreover, combination contraceptives are often considered a first-line treatment for managing endometriosis symptoms, as they are effective in providing symptom relief and are generally well-tolerated by women. They can also help in the long-term management of the condition without the adverse effects associated with more aggressive treatments.

Androgen therapy and testosterone replacement are not typically used due to their side effects and potential for exacerbating symptoms. Low-dose oral estrogen can also be problematic, as it does not provide the necessary progestin component needed to counteract the effects of estrogen on endometrial tissue. Thus, combination contraceptives emerge as the most suitable therapeutic option in the management of endometriosis symptoms.