Which medication can help in managing symptoms of fibrocystic breast disease?

• A. Amiloride
• B. Spironolactone
• C. Fluconazole
• D. Danazol

Answer: (B)

The medication that is particularly helpful in managing symptoms of fibrocystic breast disease is danazol. This medication is a synthetic androgen that can alleviate breast pain and tenderness by decreasing estrogen levels in breast tissue, which are believed to contribute to the cyst formation and associated symptoms in this condition. Danazol works by inhibiting the effects of estrogen and progesterone on the breast tissue, leading to a reduction in cyst size and pain.

While spironolactone is primarily used as a diuretic and is known to have anti-androgen effects, it is not typically the first choice for treating fibrocystic changes in breast tissue. Its beneficial impact on symptoms related to hormonal fluctuations may be limited compared to danazol, which directly targets the hormonal components involved in fibrocystic breast disease.

Fluconazole is an antifungal medication and is unrelated to the management of fibrocystic breast disease, as it does not address the hormonal factors or breast tissue alterations. Amiloride, a potassium-sparing diuretic, similarly does not play a role in managing this condition. Therefore, danazol stands out as the most appropriate choice for symptom management in fibrocystic breast disease due to its mechanism of reducing hormone levels that exacerbate