Which medication is indicated for the treatment of bladder overactivity?

• A. Oxybutynin
• B. Prazosin
• C. Metoprolol
• D. Hydrochlorothiazide

Answer: (A)

Oxybutynin is indicated for the treatment of bladder overactivity, particularly in conditions like detrusor overactivity or overactive bladder syndrome. This medication belongs to a class of drugs known as anticholinergics, which work by inhibiting involuntary bladder muscle contractions. By blocking the action of acetylcholine on muscarinic receptors in the bladder, oxybutynin helps to decrease urinary urgency and frequency, providing relief for patients with urinary incontinence.

The other medications listed do not target bladder overactivity. Prazosin is primarily used for hypertension and symptoms of benign prostatic hyperplasia; it works as an alpha-1 adrenergic antagonist. Metoprolol is a beta-blocker primarily indicated for hypertension, heart disease, and heart failure, acting on the cardiovascular system rather than the urinary tract. Hydrochlorothiazide is a thiazide diuretic used to treat hypertension and edema, focusing on fluid balance rather than bladder function. Thus, oxybutynin stands out as the appropriate choice for managing bladder overactivity.