Which of the following medications is effective against Candida albicans only?

• A. Fluconazole
• B. Spironolactone
• C. Medroxyprogesterone acetate
• D. Danazol

Answer: (A)

Fluconazole is an antifungal medication that is specifically effective against various fungi, particularly Candida albicans, which is a common cause of yeast infections. It works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby leading to cell death. Fluconazole is widely used to treat infections caused by Candida species, especially in cases of vulvovaginal candidiasis.

The other medications mentioned do not have antifungal properties. Spironolactone is a potassium-sparing diuretic and aldosterone antagonist used primarily to treat conditions like hypertension and edema. Medroxyprogesterone acetate is a progestin used in hormonal contraceptives and to manage menstrual disorders, while danazol is an androgen that is used primarily to treat endometriosis and fibrocystic breast disease. None of these options possess the antifungal activity against Candida albicans, making fluconazole the correct choice in this context.